Comparing Tear Film Viscosity between Sjögren and Non-Sjögren Dry Eye Disease

This study aimed to compare tear film viscosity (TFV) in Sjögren and non-Sjögren dry eye diseases (DEDs). was a cross-sectional observational study. A total of 68 DED patients were enrolled, including 32 with syndrome (SS) 36 without SS. TFV assessed by analyzer determined the momentary moving speed (MMS; MMS (t) = α × t−β, t time (s)) its power-law fitting-derived parameters (α β). Among four indices (MMS (0.1 s), (2.0 α, β), SS-DED had significantly lower s) (p 2.01 10−5), 0.0375), β 0.0076). The group also higher OSDI, central nasal meniscus height (TMH), OSS. correlated TMH OSS (ρ 0.2520, p 0.0381 TMH; ρ −0.3487, 0.0036 OSS). Index not any non-TFV tests. In conclusion, are promising distinguishing from non-SS-DED early. these indices, is best alternative clue for detecting SS-DED.